[12] Anticonvulsants induce some metabolic pathways suitable to docetaxel. CYP450 and CYP3A display amplified expression in response to the use of anticonvulsants along with the metabolism of docetaxel metabolite M4 is processed by these CYPs. A corresponding increase in clearance of M4 by twenty five% is observed in people using phenytoin and phen… Read More